Viral infection is a proliferation of a virus inside the body after invading normal living cells Many viral infections are asymptomatic or inapparent Iceberg Concept of Viral Infection

Three requirements for ensuring a successful infection Sufficient virus particles must be available The cells at the primary site of infection must be accessible, susceptible, and permissive The local host…

Chain of viral infection

Five types of virus infections (lytic, persistent, latent, transforming and abortive) are illustrated with emphasis on the progeny virus production and the state of the viral genome (red). The virus…

The learning objectives of studying the pathogenesis of viral infections often focus on understanding the the mechanisms that lead to disease. Specifically how how viral infections lead to cell death…

Frank Fenner’s classic study of the pathogenesis of ectromelia (mousepox) viral infection Frank Fenner’s classic study on the pathogenesis of ectromelia virus (mousepox) significantly advanced our understanding of viral infections,…

The effects of virus infection on the host cell 1-Cytocidal (death of infected cell) A cell can be directly killed by the virus, The virus kills the cell by Inhibition…

Viral oncogenesis refers to the process by which certain viruses contribute to the development of cancer. Some viruses, known as oncogenic viruses, can cause cancer by directly or indirectly disrupting…