VM 235: Veterinary Virology 2022
Group assignment
Instructions: The work should not exceed 10 pages (word format) which will be submitted as a soft copy. The work will also be presented for 10 minutes in the class on not more than 10 slides.
QUESTION
- Describe extensively the family located in your group of choice based on the following guidelines:
- Basic history of the family (when and who discovered it)
- The general structure of the viruses under the family (structure, size, the symmetry, naked or enveloped)
- The type (s) of the genomes from different viruses under the family (type of nucleic acid-ds, ss, DNA or RNA, circular or linear, and the replication site-cytoplasm or nucleus)
- What effects do the viruses cause on the host cell in the given family
- The genera and the diseases that affect animals and or humans
HINT: Use the sample of the table below to answer question number 1 (a-g). Information in this table is for demonstration only.
| Family name | Arenaviridae |
| Genome | (+) ss RNA |
| Genome size | 80-120 kbp |
| Symmetry of capsids | Icosahedral |
| Naked or enveloped | Enveloped |
| Baltimore class | Class IV |
| Virion size | 100-130 nm |
| DNA polymerase | Packaged in the virion |
| Genus and species | Orthopoxvirus: Cowpox virus, Camelpox virus
Parapoxvirus: BoPS, Orf virus, pseudocowpox virus Avipoxvirus: Fowlpox virus, turkeypox virus Capripoxvirus: Goatpox virus, LSD virus, sheeppox virus Leporipoxvirus: Rabbit fibroma Suipoxvirus: Swinepox |
| Disease(s) of veterinary and or medical importance | Lumpy skin disease, Foot and mouth disease etc |
| Hosts | Cattle (Bos taurus, zebus, domestic buffaloes) |
| Laboratory diagnosis | EM, Inoculation of primary cell culture of lamb or calf testis cells followed by HE, DIF, virus neutralization; ELISA |
| Target cells | Epithelial cells |
| Cellular Virus receptors | CD4 |
| Viral attachment ligand | Glycoprotein 120 |
| Transmission | Mechanical or insect bite |
| Reservoir host | Animals or human |
| Vector | Arthropod bite (stable fly Stomyxos calcitrans and Biomyia fasciata)) |
| Control | Homologous attenuated virus vaccine: Neethling strain
Heterologous attenuated virus vaccine: sheep pox vaccine |
| Antivirals (if available) | Zidovudine, tenofovir |
- Using a well-labeled diagram, describe the mode of replication of the viruses of veterinary and or medical importance under the family
- Describe the mode of action of the antivirals used to control disease(s) of veterinary and or medical importance under the family (if available)
THE LIST OF FAMILIES TO CHOOSE FROM
| S/No | VIRUS FAMILY | GROUP NUMBER | NAMES OF STUDENTS |
| 1 | Asfarviridae | G1 | |
| 2 | Bunyaviridae | G2 | |
| 3 | Coronaviridae | G3 | |
| 4 | Flaviviridae | G4 | |
| 5 | Iridoviridae | G5 | |
| 6 | Orthomyxoviridae | G6 | |
| 7 | Papillomaviridae | G7 | |
| 8 | Paramyxoviridae | G8 | |
| 9 | Picornaviridae | G9 | |
| 10 | Poxviridae | G10 | |
| 11 | Rhabdoviridae | G11 | |
| 12 | Retroviridae | G12 | |
| 13 | Parvoviridae | G13 | |
| 14 | Togaviridae | G14 |
ALL THE BEST!
BVM 232: Assignment 2014
Instructions: The work should not exceed 10 pages which will be submitted as a soft copy before the end of the course.
Describe extensively the family located to your name based on the following guidelines:
- Basic history of the family (how, when, who discovered)
- The general structure of the viruses under the family (structure, size, the symmetry, naked or enveloped)
- The type (s) of the genomes from different viruses under the family (type of nucleic acid-ds, ss, DNA or RNA, circular or linear, and the replication site-cytoplasm or nucleus)
- The mode of replication of the viruses under the family (diagram is essential)
- List the different methods that are used to study and identify viruses under the family
- What effects do the viruses cause on the host cell in the given family
- Using a table, list the genus and the diseases that affect the system indicated to your family and the host they infect.
- Briefly, describe one disease of importance to Tanzania under the following subheadings: pathogenesis, clinical signs, prevention, and control.