VM 235: Veterinary Virology 2022

Group assignment

Instructions: The work should not exceed 10 pages (word format) which will be submitted as a soft copy. The work will also be presented for 10 minutes in the class on not more than 10 slides.

 

QUESTION                          

  1. Describe extensively the family located in your group of choice based on the following guidelines:
  2. Basic history of the family (when and who discovered it)
  3. The general structure of the viruses under the family (structure, size, the symmetry, naked or enveloped)
  4. The type (s) of the genomes from different viruses under the family (type of nucleic acid-ds, ss, DNA or RNA, circular or linear, and the replication site-cytoplasm or nucleus)
  5. What effects do the viruses cause on the host cell in the given family
  6. The genera and the diseases that affect animals and or humans

HINT: Use the sample of the table below to answer question number 1 (a-g). Information in this table is for demonstration only.

 

Family name Arenaviridae
Genome (+) ss RNA
Genome size 80-120 kbp
Symmetry of capsids Icosahedral
Naked or enveloped Enveloped
Baltimore class  Class IV
Virion size 100-130 nm
DNA polymerase Packaged in the virion
Genus and species Orthopoxvirus:   Cowpox virus, Camelpox virus

Parapoxvirus: BoPS, Orf virus, pseudocowpox virus

Avipoxvirus:    Fowlpox virus, turkeypox virus

Capripoxvirus:   Goatpox virus, LSD virus, sheeppox virus

Leporipoxvirus:    Rabbit fibroma

Suipoxvirus:   Swinepox

Disease(s) of veterinary and or medical importance Lumpy skin disease, Foot and mouth disease etc
Hosts Cattle (Bos taurus, zebus, domestic buffaloes)
Laboratory diagnosis EM, Inoculation of primary cell culture of lamb or calf testis cells followed by HE, DIF, virus neutralization; ELISA
Target cells Epithelial cells
Cellular Virus receptors CD4
Viral attachment ligand Glycoprotein 120
Transmission Mechanical or insect bite
Reservoir host Animals or human
Vector Arthropod bite (stable fly Stomyxos calcitrans and Biomyia fasciata))
Control Homologous attenuated virus vaccine: Neethling strain

Heterologous attenuated virus vaccine: sheep pox vaccine

Antivirals (if available) Zidovudine, tenofovir

 

  1. Using a well-labeled diagram, describe the mode of replication of the viruses of veterinary and or medical importance under the family
  2. Describe the mode of action of the antivirals used to control disease(s) of veterinary and or medical importance under the family (if available)

 

THE LIST OF FAMILIES TO CHOOSE FROM

S/No VIRUS FAMILY GROUP NUMBER NAMES OF STUDENTS
1 Asfarviridae G1  
2 Bunyaviridae G2
3 Coronaviridae G3
4 Flaviviridae G4
5 Iridoviridae G5
6 Orthomyxoviridae G6
7 Papillomaviridae G7
8 Paramyxoviridae G8
9 Picornaviridae G9
10 Poxviridae G10  
11 Rhabdoviridae G11  
12 Retroviridae G12
13 Parvoviridae G13
14 Togaviridae G14  

 

ALL THE BEST!

 

 

BVM 232: Assignment 2014

Instructions:   The work should not exceed 10 pages which will be submitted as a soft copy before the end of the course.

Describe extensively the family located to your name based on the following guidelines:

  1. Basic history of the family (how, when, who discovered)
  2. The general structure of the viruses under the family (structure, size, the symmetry, naked or enveloped)
  3. The type (s) of the genomes from different viruses under the family (type of nucleic acid-ds, ss, DNA or RNA, circular or linear, and the replication site-cytoplasm or nucleus)
  4. The mode of replication of the viruses under the family (diagram is essential)
  5. List the different methods that are used to study and identify viruses under the family
  6. What effects do the viruses cause on the host cell in the given family
  7. Using a table, list the genus and the diseases that affect the system indicated to your family and the host they infect.
  8. Briefly, describe one disease of importance to Tanzania under the following subheadings: pathogenesis, clinical signs, prevention, and control.