Lesson 4: Emerging and Re-emerging viruses
Emerging and re-emerging viruses are a significant focus of study in virology, given their ability to cause widespread disease and adapt to new hosts, including humans. Emerging Viruses Emerging viruses…
Lesson 2c: Mechanisms of viral oncogenesis
Viral oncogenesis refers to the process by which certain viruses contribute to the development of cancer. Some viruses, known as oncogenic viruses, can cause cancer by directly or indirectly disrupting…
Lesson 2b: Cellular Pathogenesis
The effects of virus infection on the host cell 1-Cytocidal (death of infected cell) A cell can be directly killed by the virus, The virus kills the cell by Inhibition…
Lesson 2a: A model for studying viral pathogenesis
Frank Fenner’s classic study of the pathogenesis of ectromelia (mousepox) viral infection Frank Fenner’s classic study on the pathogenesis of ectromelia virus (mousepox) significantly advanced our understanding of viral infections,…
Lesson 1d: Types and patterns of viral infections
Five types of virus infections (lytic, persistent, latent, transforming and abortive) are illustrated with emphasis on the progeny virus production and the state of the viral genome (red). The virus…
Lesson 1c: Chain of viral infection
The chain of viral infection describes the process by which a virus moves from one host to another, ultimately causing disease. It includes several key stages, from the initial contact…
Lesson 1b: Sequence of Virus Spread in the Host Organs
The sequence of virus spread within a host involves the movement of the virus from its point of entry to various tissues and organs. The process, known as viral dissemination,…
Lesson 1a: Mechanisms of viral infections
Three requirements for ensuring a successful infection Sufficient virus particles must be available The cells at the primary site of infection must be accessible, susceptible, and permissive The local host…
Lesson 5 (c): Virus Internalization (Receptor-mediated endocytosis or Veropexis)
Endocytosis or veropexis is the most common cellular entry technique for viruses Once the cell internalizes the virus, it is then delivered to an acidic pit, a so-called early endosome.…