Virus Penetration: How do they overcome the plasma and nuclear membrane?
The viral genome needs to get to the cytoplasm or to the nucleus for the virus that replicates in the nucleus. In other words, the viral nucleocapsid has to overcome…
Towards the commemoration of the World Rabies Day September 28 – Things to ponder
Introduction Rabies is a viral disease that causes encephalitis in humans and other mammals whose main symptoms include fever and tingling at the site of exposure, nausea, vomiting, violent movements,…
What is the difference between virus isolate, variant, strain, serotype, topotype and genotype?
There are a number of necessary terminologies generally utilized in virology and ought to be clearly outlined to be in the identical understanding amongst scientists in addition to different folks…
Why is it difficult to control African Swine fever in Tanzania?
Introduction African swine fever virus (ASFV) is a double stranded DNA virus of the family Asfaviridae and genus Asfivirus that causes African swine fever (ASF). The disease can lead up…
How are the RBCs used for HA and HI prepared?
Hemagglutination assay and hemagglutination inhibition test (covered in the diagnostic virology) are very important assay Virology. Both use red blood cells where some viruses tend to bind on the sialic…
Interactions of hemagglutinins with sialic acids receptors
What’s a hemagglutinin? Orthomyxoviruses include envelope-associated proteins, hemagglutinin (HA) and neuraminidase (NA) inserted into the lipid bilayer and protruding on the floor as spikes. The hemagglutinin glycoprotein (HA) performs vital…
Endocytic pathways for virus internalization
Viruses use a number of advanced and fewer understood mechanisms and pathways to ship their cargo (nucleocapsid and accent proteins) to the cytoplasm and or nucleus. Ari Helenius was the…