SOKOINE UNIVERSITY OF AGRICULTURE
COLLEGE OF VETERINARY AND MEDICAL SCIENCES
DEPARTMENT OF MICROBIOLOGY, PARASITOLOGY AND BIOTECHNOLOGY
PROBATION/FIRST SITTING UNIVERSITY EXAMINATION SEPTEMBER 2024
EXAMINATION PAPER: VETERINARY VIROLOGY (VM 235)
PROGRAMME: BACHELOR OF VETERINARY MEDICINE
DATE: 17th SEPTEMBER 2024
TME ALLOWED: 15:00 – 18:00
VENUE: VET 06
EXAMINATION NUMBER: ……………………………………
Instructions to Candidates
- Answer ALL questions
- Take note of the mark’s distribution
- Observe all instructions in your answer book
- Observation of General University Examinations Regulations is vital
QUESTION ONE (25 Marks)
a) Discuss the fundamental differences between viruses and cellular organisms (10 marks)
b) With one example for each type, describe the three main types of viral symmetry (15 marks)
QUESTION TWO (25 Marks)
Write short notes on the following:
a) Virus envelopes (10 marks)
b) Classified of viruses based on their genome (15 marks)
QUESTION THREE (25 Marks)
a) Describe the stages of the virus replication cycle (20 marks)
b) Explain the role of reverse transcriptase in retroviruses (5 marks)
QUESTION FOUR (25 Marks)
Discuss the principles behind the different vaccine types for viral diseases in livestock
QUESTION FIVE (25 Marks)
- Discuss the mechanisms by which antiviral agents inhibit viral replication (18 marks)
- What are the factors that contribute to the development of antiviral resistance in viruses (7 marks)
QUESTION SIX (25 Marks)
Compare and contrast the mechanisms of virus entry and release in enveloped versus non-enveloped viruses
QUESTION SEVEN (25 Marks)
a) Explain the role of host cell machinery in the replication of viruses (20 marks)
b) Describe the process of reverse transcription in retroviruses (5 marks)
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