Lesson 5 (a): Virus Internalization (Phagocytosis)

Bycaptainhabari

August 11, 2024

 

Phagocytosis

  • Phagocytosis (cell eating) – occurs in specialized mammalian cells (so-called professional phagocytes, e.g., dendritic cells and macrophages) that engulf large and essential particles.
  • Viral entry by this pathway typically involves the formation of large extracellular projections, and the internalized virus is taken into a phagosome.
  • Actin and RhoA are typically necessary for this process.