BLS 113 UE July 2023

SOKOINE UNIVERSITY OF AGRICULTURE

COLLEGE OF VETERINARY AND MEDICAL SCIENCES

UNIVERSITY EXAMINATION FOR 1st YEAR BACHELOR OF BIOTECHNOLOGY AND LABORATORY SCIENCES

DATE: 25th July 2023

TIME: 3:30-6:30 pm

INSTRUCTIONS: ATTEMPT ALL QUESTIONS
Use well labeled diagrams where necessary

VENUE: ENG 5 and 7

QUESTION ONE (25 Marks)

a) Describe the structure and components of viruses (13 marks)
b) State how the structure and components of viruses are used for naming and classifying viruses (12 marks)

QUESTION TWO (25 Marks)

Explain the process of viral entry into host cells and the mechanisms viruses employ to evade the host immune system.

QUESTION THREE (25 Marks)

Compare and contrast the replication strategies of DNA and RNA viruses, providing one example of each.

QUESTION FOUR (25 Marks)

a) Discuss the mechanisms by which antiviral drugs target viral replication (18 marks)
b) How did HIV resistance to Zidovudine (azidothymidine, AZT) develop? (7 marks)

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