Fast-spreading mutation helps common flu subtype escape immune response

Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein. Source link

Effects of Genital Warts

A lot of people fear this virus because there is no cure for the HPV virus. Treatment available is only the removal of the warts but not the virus so recurrence is possible. This...

5 Useful Home Remedies for a Cough

General coughing is entirely natural and helps clear irritants or phlegm from your throat. But, a period of sustained coughing can be a problem and may relate to a variety of conditions, such as...

Study highlights multiple health risks among a people living longer with HIV

The impact and prevalence of heart disease and other critical comorbidities on an aging global population with human immunodeficiency virus (HIV) have emerged from a suite of articles in The Journal of Infectious Diseases...

Peking University and Tsinghua University: Postdoctoral Positions at Center for Life Sciences

Competitive salary and benefits: Peking University and Tsinghua University: Postdoctoral Positions at Center for Life Sciences   As an integral part of the Chinese efforts to build first-rate universities, the Center for Li… Beijing...

Genotyping of 30 kinds of cutaneous human papillomaviruses by a multiplex microfluidic loop-mediated isothermal amplification and visual detection method

Human papillomaviruses (HPVs), a group of non-enveloped small viruses with double-stranded circular DNA which lead to multiple skin diseases such as benign warts, are commonly seen in clinics. The current HPV … Source link

Experts, advocates publish guidance for research on HIV, co-infections in pregnancy

Pregnant women are among those most in need of safe and effective preventives and treatments for HIV and co-infections. Yet because they are commonly excluded from research, they are among the least likely to...

Reduction of Salmonella contamination on the surface of chicken skin using bacteriophage

Enteric infections caused by Salmonella spp. remain a major public health burden worldwide. Chickens are known to be a major reservoir for this zoonotic pathogen. The presence of Salmonella in poultry farms and a…...

Novel transcription regulatory sequences and factors of the immune evasion protein ICP47 (US12) of herpes simplex viruses

Herpes simplex virus (HSV) can cause encephalitis. Its infected cell polypeptide 47 (ICP47), encoded by immediate-early gene US12, promotes immune escape. ICP47 was modified in the clinically approved oncolytic H… Source link

Skin Tag Removal – Natural Or Clinical

What exactly are skin tags, and what is the best method for skin tag removal – natural or clinical? Skin tags are those odd little skin growths that may be shaped like a piece...

Prevalence and genotype distribution of HPV and cervical pathological results in Sichuan Province, China: a three years surveys prior to mass HPV vaccination

HPV persistent infection is a strong carcinogenic factor that can induce cervical cancer. Investigation of HPV epidemiology and genotype distribution is of great meaning for the development of cervical cancer … Source link

Herbal Medicine – Part III – Aloe Vera – A Case Study

History of Aloe Vera The aloe plant most likely originated in the semi-arid regions of Africa. It was used by the ancient Sumerians, Egyptians, and Greeks in the healing of wounds. Alexander the Great...

Biologists trace plants' steady mitochondrial genomes to a gene found in viruses, bacteria

Biologists have traced the stability of plant mitochondrial genomes to a particular gene – MSH1 – that plants have but animals don’t. Their experiments could lend insight into why animal mitochondrial genomes tend to...

TWiV 636: Georgia State viral

From Georgia State University, Vincent speaks with Chris, Andrew, Priya, and Richard about their careers and their work on Ebolaviruses, rotavirus, and antiviral drug development. Click arrow to playDownload TWiV 636 (68 MB .mp3, 113...

TWiV 637: Clearing the fog of ignorance

In this episode, approval of an Ad5 vectored SARS-CoV-2 vaccine for the military in China, description and clinical trials of a Novavax vaccine joining Operation Warp Speed, prevalence of SARS-CoV-2 in Spain, shedding and...

Structural analysis of COVID-19 spike protein provides insight into its evolution

Researchers have characterized the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved and could help inform...

Causes of Water Retention – 10 Common Reasons For Swelling of the Body

Water retention is a common health problem that greatly affects the day to day activities of the sufferers. Water retention – medically referred to as edema – is the accumulation of excess fluid that...

Researchers make first steps toward a cure for HIV

Researchers have developed a way to pull HIV out of the latent reservoir making the virus visible to the immune system and providing the potential to be killed by treatment. Source link

No evidence for increased human transmission of SARS-CoV-2

Don’t believe the headlines that SARS-CoV-2 is becoming more transmissible! Virologists are making conclusions that are not justified by the data. SARS-CoV-2 virus isolates from many parts of the world have a single amino...

Bats offer clues to treating COVID-19

Bats carry many viruses, including COVID-19, without becoming ill. Biologists are studying the immune system of bats to find potential ways to ‘mimic’ that system in humans. Source link

Global wildlife surveillance could provide early warning for next pandemic

Researchers propose a decentralized, global wildlife biosurveillance system to identify — before the next pandemic emerges — animal viruses that have the potential to cause human disease. Source link

Trial By Error: Excellent News Coverage of UK Genetics Study in The Times

By David Tuller, DrPH Note: The DecodeME team held a Facebook Q-and-A this week. If you want more information about the study, you can watch the video here. Two major UK government funding agencies...

Repurposing public health systems to decode COVID-19

New research describes how national surveillance systems can be linked with the UK Biobank. This pooled data could then be used to understand how genetics and other epidemiological factors impact risk of developing severe...

Different Things You Can Do With Sweet Potatoes

In Pakistan, sweet potatoes, or shakarkandi as they are called in Urdu, are mainly used in dessert recipes. They are usually very sweet and a pale to rich orange in colour when cooked. However...

What Is Osteoarthritis and What Can Be Done About It?

Osteoarthritis (OA) is the most common form of arthritis and affects approximately 28 million Americans. While it was initially viewed as a “wear and tear” phenomenon, it has become quite clear that it is...

Relapsing viral keratoconjunctivitis in COVID-19: a case report

Since the outbreak of Coronavirus Disease 2019 (COVID-19) in December 2019, many studies have reported the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the conjunctival sac of pa… Source link

Longitudinal transcriptomic characterization of viral genes in HSV-1 infected tree shrew trigeminal ganglia

Following acute infection, Herpes Simplex virus-1 (HSV-1) establishes lifelong latency and recurrent reactivation in the sensory neurons of trigeminal ganglia (TG). Infected tree shrew differs from mouse and s… Source link

Nurses and midwives take the lead in providing HIV services in Eastern and Southern Africa

“Nurse-initiated and managed antiretroviral therapy” (NIMART) is an innovative approach to making effective medications more accessible to people living with HIV (PLWH) in low-resource countries. A new study identifies challenges and opportunities to promoting...

Researchers create air filter that can kill the coronavirus

Researchers have designed a ‘catch and kill’ air filter that can trap the virus responsible for COVID-19, killing it instantly. Source link

How to Get Rid of Acne Cyst

Cyst is a severe form of acne. Cysts are hard lumps under the skin. They are found in people, regardless of gender and age. The cysts are characterized by the presence of pus inside....

The newly emerged COVID-19 disease: a systemic review

Coronaviruses are large family-RNA viruses that belong to the order Nidovirales, family Coronaviridae, subfamily Coronavirinae. The novel COVID-19 infection, caused by a beta coronavirus called SARS-CoV-2, is a n… Source link

New platform technology can rapidly disrupt existing biofilms that account for chronic diseases

Chronic and recurrent bacterial diseases are treatment-resistant due to the ability of the pathogens to establish biofilms, which act as fortresses built of extracellular DNA and proteins to protect populations of the bacteria. Source...

How to Cure Hemorrhoids Right in Your Home

Are you looking for ways on how to cure hemorrhoids but are too ashamed to let anybody, not even your doctor, know that you have them? This is actually a very common dilemma among...

How to Stay Healthy on Your Travels

Keeping an eye on your health and looking after yourself is important when you’re traveling. You don’t want to miss a thing and that means staying on top form; to give you a helping...

Long-acting injectable form of HIV prevention outperforms daily pill in NIH study

A pre-exposure prophylaxis (PrEP) regimen containing an investigational long-acting form of the HIV drug cabotegravir injected once every 8 weeks was more effective than daily oral Truvada at preventing HIV acquisition among cisgender men...

Flu in early life determines our susceptibility to future infections

Early infections of influenza A can help predict how the virus will affect people across different ages in the future and could impact the effectiveness of flu vaccines, says a new study. Source link

Doctors say experimental treatment may have rid man of HIV

A Brazilian man infected with the AIDS virus has shown no sign of it for more than a year since he stopped HIV medicines after an intense experimental drug therapy aimed at purging hidden,...

Characterization of neuraminidase inhibitor-resistant influenza virus isolates from immunocompromised patients in the Republic of Korea

The emergence of influenza viruses resistant to anti-influenza drugs is a threat to global public health. The Korea Centers for Disease Control and Prevention operates the Korea Influenza and Respiratory Virus… Source link

Pulmonary endothelium-derived PD-L1 induced by the H9N2 avian influenza virus inhibits the immune response of T cells

The PD-1/PD-L1 pathway is an inhibitory signaling pathway that maintains the balance between the immune response and immunotolerance, and its overactivation in cancer and viral infections inhibits T cell funct… Source link

Impact of pyriproxyfen on virus behavior: implications for pesticide-induced virulence and mechanism of transmission

More than 3 years since the last Zika virus (ZIKV) outbreak in Brazil, researchers are still deciphering the molecular mechanisms of neurovirulence and vertical transmission, as well as the best way to control… Source...

Why Chronic Inflammation Is Common Now: Physiology of Hypoxia, Blood Gases and Ineffective Breathing

Inflammation, as a normal physiological response Inflammation is part of the complex biological reaction of the human organism involving the immune system, blood vessels, and effects related to changes in hormones and many other...

AIDS report: Kids are lagging and COVID-19 is harming care

New numbers on the global AIDS epidemic show some big successes, such as fewer deaths and new infections. But there are also some tragic failures: Only half the children with HIV, the virus that...

Treatment For Brain Tumors

Many persons with brain cancers want to know everything regarding their disease as well their treatment. Nevertheless, stress and shock after diagnosis of brain cancer may make it harder for everything. The patient really...

Skin Tag Treatment

Do you have a skin tag in your face? Do you see this growth as unaesthetic and you want to get rid of it? If you want to know some tag treatments, you may...

Acupuncture and Herbs for Heartburn and Indigestion

Many people experience heartburn and acid reflux from time to time. This happens when acid from the stomach washes back into the esophagus. When this tendency to have heartburn becomes chronic, and your doctor...

TWiV 635: Mask hysteria

Daniel Griffin provides a clinical update on COVID-19, then we review SARS-CoV-2 shedding in children, how to resume school safely, the need for widespread testing and wearing face masks, and much more, including listener...

Stage 3 Colon Cancer – Herbal Therapy Without Chemotherapy Or Radiotherapy

Tan (M-73) was 50 years old when she was diagnosed with colon cancer. Prior to her diagnosis Tan had been passing out blood in her stools. She took various kinds of herbs but they...

Irritable Bowl Syndrome and Food Allergies

Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder with a reported prevalence of 12%-22% in the general population. In fact, IBS is the most common diagnosis made by gastroenterologists in the...

Genital Wart Cream

Genital warts are a extremely contagious sexually transmitted disease, and the prevalence of this condition is at record highs. The latest figures released from the CDC are showing us that nearly 80% of the...

TGMC:Lore

Moff ← Older revision Revision as of 02:35, 5 July 2020 Line 206: Line 206:   <br>   <br>     − ==2415-2470==   + ==2415-2470==   (TGMC PRESENT DAY)-     (TGMC PRESENT...

Mesothelioma Symptoms And Sign

Early symptoms of mesothelioma may not appear until 20 to 50 years (or more) after exposure to asbestos. Shortness of breath, cough, and pain in the chest due to the accumulation of fluid in...

How To Get Rid Of Phlegm In Throat And Chest

Phlegm in Throat Phlegm in throat is normal in healthy human beings, and its purpose is to filter the air we breathe by trapping tiny particles, like dust, and preventing them from entering our...

Trial By Error: Nudge for BMJ About Music Therapy; Letter to “Health Anxiety” Expert

By David Tuller, DrPH I have written two more letters and have posted them below. The first letter is a nudge to BMJ’s research integrity department, which missed a deadline this week for providing...

Cirrhosis – Effects and Conditions

Cirrhosis is the irreversible scarring, due to excessive consumption of alcohol or a viral infection like hepatitis C, of the liver. This usually happens during the end stages of severe liver disorders. The normal...

Promising application of monoclonal antibody against chikungunya virus E1-antigen across genotypes in immunochromatographic rapid diagnostic tests

Three different genotypes of chikungunya virus (CHIKV) have been classified: East/Central/South African (ECSA), West African (WA), and Asian. Previously, a rapid immunochromatographic (IC) test detecting CHIKV… Source link

HIV may not worsen COVID-19 outlook

People with HIV who were hospitalized with COVID-19 didn’t have worse results than COVID-19 patients without HIV, new research shows. Source link

Anaplasmosis bacterium tinkers with tick's gene expression to spread to new hosts

For the first time, scientists have shown that the bacterium that causes the tick-borne disease anaplasmosis interferes with tick gene expression for its survival inside cells and to spread to a new vertebrate host....

NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population

SLC10A1 gene codes NTCP, a receptor through which the hepatitis B virus (HBV) gets access into hepatocytes – a stage of the viral cycle necessary for replication. Polymorphism variants of SLC10A1 play roles in…...

History of Crohns Disease

Crohn?s disease, a disease belonging to the larger group of inflammatory bowel diseases (IBD), is named after an American gastroenterologist, Dr. Burrill B. Crohn. Crohn’s disease initially came to be known as a medical...

Herbal Homeopathic Treatment of Gout

Arthritis is one of the main diseases of bones and joints. It limits your movement and is mostly evident in older people. There is more than one type of arthritis. You can suffer from...

University of California, Davis, CA: Postdoctoral Researcher

commensurate with qualifications and experience.: University of California, Davis, CA: POSTDOCTORAL POSITION ENCAPSULATED CRISPR GENE-EDITOR FOR MUCOSAL DELIVERY Location: The Department of Molecular and Cellular Biology, University o… Davis, California Source link

Smart structures: Structural cells of the body control immune function

Researchers analyzed the epigenetic and transcriptional regulation in structural cells. They found widespread activity of immune genes, suggesting that structural cells are deeply involved in the body’s response to pathogens. Moreover, the study uncovered...

TWiV 634: 1000 hours of the sunlight of TWiV

TWiV reviews a new H1N1 swine influenza virus from China with pandemic potential, Ad5 vectored SARS-CoV-2 oral vaccine candidate, Operation Warp Speed vaccine candidates, FDA guidance on vaccine approval, and answer listener email. Click...

The role of children in transmission of SARS-CoV-2

by Gertrud U. Rey It is well established that children experience less severe disease after infection with SARS-CoV-2. However, to what extent infected children contribute to transmission of the virus is less clear. This topic...

Mitomycin, 5-fluorouracil, leflunomide, and mycophenolic acid directly promote hepatitis B virus replication and expression in vitro

Reactivation of hepatitis B virus is a common complication that occurs in patients with hepatitis B virus (HBV) infection who have received cytotoxic chemotherapy or immunosuppressive therapy. This clinical ph… Source link

Experimental immunization of mice with a recombinant bovine enterovirus vaccine expressing BVDV E0 protein elicits a long-lasting serologic response

Bovine viral diarrhea virus (BVDV) is a cause of substantial economic loss to the cattle industry worldwide, and there are currently no effective treatment or preventive measures. Bovine enterovirus (BEV) has … Source link

Discover the Latest Chronic Bad Breath Cure

Bad breath is a health risk that should not be taken lightly. It affects not just the person with problem, but also people around him or her. Addressing this problem is better than making...

An HIV drug you only take twice a year?

(HealthDay)—Scientists are reporting an early step toward an HIV drug that could potentially be taken only a couple of times per year. Source link

Trial By Error: Now There’s CBT for ‘Health Anxiety’ in CFS

By David Tuller, DrPH In late December, the International Journal of Clinical and Health Psychology published an article called “Prevalence and treatment of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and co-morbid severe health anxiety.” This paper,...

How to Spot Bad Mole?

How to spot malignant mole? This morning you took a bath. The warm water feels so nice during the cold winter day. There was some funny skin itching on you back. You looked in...

What To Expect When You Suspect Breast Cancer

Breast cancer can be frightening, but knowledge is power. If you’ve been vigilant in your personal breast exams and mammograms there may come a time when a lump or suspicious area is found. The...

Scientists confirm usually harmless virus attacks the heart's electrical system

Researchers studying how a usually benign virus attacks the human heart with sometimes fatal consequences determined that the virus disrupts the heart’s electrical system – and with dual impacts not previously recognized. Source link

Natural Pneumonia Treatment – Part 1

Pneumonia is a serious infection of the lungs that can be caused by any of a number of different infectious agents, including viruses, bacteria, fungi, protozoa, and mycoplasma. The infection causes tiny air sacs...

Trial By Error: A Few Interesting Studies

By David Tuller, DrPH I’m always highlighting dodgy research from the CBT/GET ideological brigades. These studies are fun to tear apart (metaphorically and sometimes literally), but it’s also nice to be able to recommend...

Five Top Home Remedies For Pupp Rash Relief

Pupp rash is a very itchy skin condition that some women develop during the third semester of pregnancy. It also can occur at an earlier stage of pregnancy. Many women find it arises in...

TWiV 633: Singapore viral

From DukeNUS Medical School, Vincent speaks with Ashley, Sheemei, Eng Eong and Dahai about their careers and their research on flaviviruses and sensing of viral RNA. Click arrow to playDownload TWiV 633 (56 MB .mp3,...

Human myoma tissue-based extracellular matrix models for testing the effects of irradiation on the HPV positive cells

This study was designed to investigate the invasion of human papillomavirus (HPV) positive human cervical carcinoma cell lines in human leiomyoma-based extracellular matrices in vitro, and to test the suitability… Source link

Evaluation of SARS-CoV-2 viral RNA in fecal samples

The need for timely establishment of a complete diagnostic protocol of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is demanded worldwide. We selected 15 positive novel coronavirus disease 19 (… Source link

Expansion Of Pharmaceutical Plants Along With Pharmaceutical Engineering

Pharmaceutical engineering and biomedical science have become the indispensable part of Pharmaceutical plants showing their proficiency in the medical world. The main objective of biomedical science is to provide valuable pharmaceutical solutions by developing...

New study shows how tests of hearing can reveal HIV's effects on the brain

Even with effective anti-retroviral therapy, patients infected with the Human Immunodeficiency Virus (HIV) sustain central nervous system damage. Whether these problems can be mainly attributed to the disease, its treatments, or the body’s immune...

Top 10 Possible Reasons for Getting Dental Caries

Everybody wants to have strong, pearly white teeth so that they can have a best smile – but what if caries attack? Also known as dental caries, karies or cavities, this is a condition...

Study shows women are more likely to be prescribed with opioid analgesics

Women are significantly more likely to receive prescriptions of opioid analgesics. Read the study, which was performed in a nationally representative sample of adults in the U.S., in Journal of Women’s Health. Source link

Different Types of Brain Tumors

Recent studies by the American Cancer Society shows that the death rates from cancer have lowered significantly in recent years. It is now 20% lower than its peak in 1991. While scientists still have...

Psoriasis Cures and Treatments

Perhaps you have seen someone or you know someone who has psoriasis. Their skin may have red, raised patches or even lesions that are covered with whitish silver flakes that are dead skin cell...

Understanding Arthritis and How to Live Pain Free

One of the most common types of joint conditions is arthritis, which is an inflation of the joints of the body. While arthritis is the most common disability in persons above fifty-five years of...

TWiV 632: Countering a miasma of anti-think

Daniel Griffin provides a clinical update on COVID-19, then we review SARS-CoV-2 infections in non-humans, vesicular stomatitis in Kansas horses, and answer listener questions. Click arrow to playDownload TWiV 632 (87 MB .mp3, 144 min)Subscribe...

Facts About Skin Cancer

What is skin cancer? It is a malignant neoplasm of the skin. This can be fatal if left untreated for any length of time. It is very important that if a person has any...

Understanding Medical Lab Test Reports

Introduction Departments of Medical lab A standard medical or pathology lab consists of following departments: Hematology Study of blood, blood forming organs and diseases of blood Clinical pathology Includes test on urine and stool...

Breast Cancer Symptoms You Want to Know About

Breast cancer symptoms vary, and may not be the same from person to person. You may experience some, or even none or all of the common symptoms. This is why it’s important to get...

Trial By Error: My Letter to Author of CODES Commentary

By David Tuller, DrPH Earlier today, I sent the following letter to Dr David Perez, a neurologist and psychiatrist at Massachusetts General Hospital in Boston. Dr Perez, an expert on functional neurological disorders, wrote...

Detection of Human polyomavirus 2 (HPyV2) in oyster samples in northern Brazil

Human polyomavirus 2 (HPyV2 or JCPyV) is persistent in the environment due to its excretion in urine and feces; it is detected in samples of wastewater, surface water and drinking water. A lack of...

Designer peptides show potential for blocking viruses, encourage future study

Chemically engineered peptides could prove valuable in the battle against some of the most persistent human health challenges. New findings demonstrate how researchers can engineer peptides capable of selectively and specifically binding to polysialic...

Prevalence characteristics of cervical human papillomavirus (HPV) infection in the Zhoupu District, Shanghai City, China

Human papillomavirus (HPV) infection is the leading cause of genital diseases. It can cause a series of cervical lesions. The distribution of HPV genotypes indicates that the increased prevalence of high-risk … Source link

What Exhibits Congenital Or Embryonic Rest to Cause Endometriosis?

As we mentioned in previous articles, during the last stage of the menstrual cycle normally a layer of endometriosis lining in the inside of the uterus is expelled, known as menstruation blood but instead...

The Color of Experience

George Gallo’s film, “Local Color” has taken the word riveting and has successfully raised its meaning to a new charted height, for this film has opened my eyes more, and has given me the...

User:Iatots

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The OTC Genital Wart Treatment

There are different ways to take off genital warts from the skin. The most common option people use the application of topical medications. Over the counter drugs are usually made for topical applications. Over...

HPV Treatment for Men

Men play a critical role in the transmission of HPV, and in order to decrease HPV exposure and the risk of cervical cancer in women, the problem of HPV infection in men must be...

Trial By Error: CODES Trial Commentary Promotes ‘Eminence-Based Medicine’

By David Tuller, DrPH By all accounts, the recently published CODES trial was the most authoritative study to date of whether cognitive behavior therapy (CBT) was an effective treatment for so-called dissociative seizures–a point...

X-rays size up protein structure at the 'heart' of COVID-19 virus

Researchers have performed the first room temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce. It marks an important first step in the ultimate goal of...

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